Ext. 2622

jsaucedo@yachaytech.edu.ec

Biografía

Juan Pablo Saucedo Vázquez obtained a PhD in Chemical Sciences from the Universidad Nacional Autónoma de México (Prof. Martha Sosa group, UNAM, México) and in 2012 focused on the study of reaction mechanism of the oxidative dehydrogenation of amines activated by iron(III) in coordination compounds. In 2015 Professor Saucedo made a Postdoctoral Research at the Cellular Physiology Institute of UNAM (Prof. Wilhelm Hansberg group) on the study of the redox and spectroscopic properties of the bifunctional enzyme catalase-peroxidase CAT-2 from Neurospora crassa fungi. In 2015 he was honored as a member of the National Research System level 1 (CONACyT-México) as recognition of his career.

Summary of Interests

My research interests span the study of the activation of small inorganic molecules such as O2, N2, H2O2, NO, by inorganic and biological systems containing iron and/or copper metals as active center. I
have a special interest in metallo-proteins of natural origin (fungi, plants, bacteria) with metal cofactors and the use of spectro-electrochemistry techniques and the Electron Paramagnetic Resonance (EPR) spectroscopy to characterize these systems.

Current Research Projects

Small molecules activation: ferryl (FeIV=O) and ferroyl (FeV=O) key intermediates in the activation of dioxygen by iron in biological and synthetic systems.

Selected Publications

•  “Synthesis, Structure, and Characterization of Molybdenum(VI) Imido Complexes with N-salicylidene-2-aminothiophenol”. Minelli, Martin; Hart-Cooper, William; Sinnwell, Joseph; Blumberg, Drew; Guzei, Ilia; Spencer, Lara; Saucedo-Vazquez, Juan Pablo; Solano-Peralta, Alejandro; Sosa-Torres, Martha. Polyhedron, 2018. DOI: 10.1016/j.poly.2018.02.017.
• “Structure, Kinetics, Molecular and Redox Properties of a Cytosolic and Developmentally Regulated Fungal Catalase-Peroxidase”. Vanessa Vega-García, Adelaida Díaz-Vilchis, Juan-Pablo Saucedo-Vázquez, Alejandro Solano-Peralta, Enrique Rudiño-Piñera, Wilhelm Hansberg. Archives of Biochemistry and Biophysics, 2018, 640, 17–26. DOI: 10.1016/j.abb.2017.12.021
• “The nitric oxide production in the moss Physcomitrella patens is mediated by nitrate reductase”. Rigoberto Medina-Andrés, Alejandro Solano-Peralta, Juan Pablo Saucedo-Vázquez, Selene Napsucialy-Mendivil, Jaime Arturo Pimentel Cabrera, Martha Elena Sosa-Torres, Joseph G. Dubrovsky and Verónica Lira-Ruan. Plos One, 2015, 10 (3), e0119400. DOI: 10.1371/journal.pone.0119400
• “Role of Molecular Oxygen in the Iron (III)-Promoted Oxidative Dehydrogenation of Amines”. Juan Pablo Saucedo-Vázquez, Peter M.H. Kroneck, Martha Elena Sosa-Torres. Dalton Trans. 2015, 44 (12), 5510. DOI: 10.1039/c4dt03606a
• “The Magic of Dioxygen” in “Sustaining Life on Planet Earth: Metalloenzymes Mastering Dioxygen and Other Chewy Gases” Volume 15 of the series Metal Ions in Life Sciences. Kroneck P., Saucedo-Vázquez J.P. Sosa Torres M. E. Series editors: Astrid Sigel, Helmut Sigel and Roland Sigel; Springer SBM, Dordrecht, the Netherlands; 2015, pp 1-12. DOI: 10.1007/978-3-319-12415-5_1
• “The Membrane-Bound Quinohemoprotein Alcohol Dehydrogenase from Gluconacetobacter diazotrophicus PAL5 Carries a [2Fe-2S] Cluster”. S. Gómez-Manzo, A. Solano-Peralta, J. P. Saucedo-Vázquez, J. E. Escamilla-Marván, PMH Kroneck, M. E. Sosa-Torres. Biochemistry. 2010, 49 (11), 2409-2415. DOI: 10.1021/bi9015007
• “On the Mechanism of Iron (III) -Dependent Oxidative Dehydrogenation of Amines.” Juan Pablo Saucedo-Vázquez, V. M. Ugalde-Saldívar, A. R. Toscano, P. M. H. Kroneck, M. E. Sosa-Torres. Inorg. Chem. 2009, 48 (3), 1214-1222. DOI: 10.1021/ic8016968
• “Magnetic and high-frequency EPR studies of an octahedral Fe (III) compound with unusual zero field splitting parameters”. A. Solano-Peralta, R. Escudero-Derat, J. P. Saucedo-Vázquez, H. El-Mkami, G. M. Smith, P-M.H. Kroneck, M.E. Sosa-Torres, Dalton. Trans. 2009, 1668-1674. DOI: 10.1039/b814225d